Turn Smart Guides on and off while drawing a path with the Pen Tool in Ai

When drawing a path, Smart Guides can come in handy to align some Anchor Points, but most of the time I need to mix aligned an non aligned points. In that case, it would be very convenient to be able to turn on Smart Guides  (cmd-U), while keeping the Pen Tool active. Right now, activating or deactivating the Smart Guides breaks the path.